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颈动脉内血流动力学特征受向前加速度影响的数值模拟
引用本文:刘岩,孙安强.颈动脉内血流动力学特征受向前加速度影响的数值模拟[J].北京航空航天大学学报,2019,45(3):493-498.
作者姓名:刘岩  孙安强
作者单位:北京航空航天大学生物与医学工程学院,北京100083;北京航空航天大学航空科学与工程学院,北京100083;北京航空航天大学生物医学工程高精尖创新中心,北京102402;北京航空航天大学生物与医学工程学院,北京100083;北京航空航天大学生物医学工程高精尖创新中心,北京102402
基金项目:国家自然科学基金(11472031,11102014)
摘    要:人们在日常或某些特殊条件下常会面临方向和大小发生迅速变化的加速度环境,已有研究发现加速度环境会影响心血管系统生理、病理特征。利用计算机模拟方法详细研究了向前加速度环境下人体颈动脉内的血流动力学参数变化规律。结果表明:加速度会对颈动脉内压力、压力梯度、壁面剪切应力等与血管生理、病理现象密切相关的血流动力学参数产生显著影响。研究结果为加速度环境下颈动脉生理、病理研究提供了一定的理论依据,也为航空航天领域加速度环境下人员防护提供参考。 

关 键 词:加速度  颈动脉  血流动力学特征  血流量  压力梯度
收稿时间:2018-08-10

Influence of forward acceleration on hemodynamic characteristics of carotid arteries:A numerical simulation
LIU Yan,SUN Anqiang.Influence of forward acceleration on hemodynamic characteristics of carotid arteries:A numerical simulation[J].Journal of Beijing University of Aeronautics and Astronautics,2019,45(3):493-498.
Authors:LIU Yan  SUN Anqiang
Institution:1.School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China2.School of Aeronautic Science and Engineering, Beihang University, Beijing 1000833.Beijing Advanced Innovation Centre for Biomedical Engineering, Beihang University, Beijing 102402, China
Abstract:Humans are usually subjected to acceleration with fast changing directions and magnitude in ordinary or some special situations. Previous studies have found that acceleration had physiological and path-ological influence on cardiovascular system. However, more in-depth investigations need to be done at present. In this study, the computer simulation method was used to study the hemodynamic parameter variation features laws of carotid artery under forward acceleration condition. The results reveal that acceleration has significant influence on the hemodynamic parameters including pressure, pressure gradient, wall shear stress, etc. in carotid artery, which have close relationship with physiological and pathological behavior of artery. This study provides theoretical basis for the research of carotid artery physiology and pathology under acceleration conditions, and also gives reference for human protection under acceleration conditions in aeronautic and astronautic fields.
Keywords:acceleration  carotid artery  hemodynamic characteristics  blood flow rate  pressure gradient
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