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| 可体内降解的骨固定材料的制备研究 | |
| 引用本文： | 史晓林,谢怀勤,张贞浴.可体内降解的骨固定材料的制备研究[J].北京航空航天大学学报,2003,29(2):144-146. |
| 作者姓名： | 史晓林 谢怀勤 张贞浴 |
| 作者单位： | 1. 哈尔滨工业大学 材料科学与工程学院; 2. 黑龙江大学 化学化工学院 |
| 摘 要： | 为制备强度和韧性都适中且可体内降解的骨固定材料,首先借助聚D,L丙交酯与聚己内酯的扩链反应获得一系列扩链反应聚合物;然后通过测定聚合物拉伸强度和降解性能随扩链剂和扩链反应条件的变化规律,来选择扩链剂和制定最佳制备工艺.利用按上述方法选定的扩链剂和制备工艺,最终制备出了拉伸强度为24.47MPa,延伸率为1091%,降解时间为6个月,且对人体无害的骨固定材料. |
| 关 键 词： | 骨固定材料 制备 聚己内酯 聚D L丙交酯 生物降解材料 |
| 文章编号： | 1001-5965(2003)02-0144-03 |
| 收稿时间： | 2001-12-04 |
| 修稿时间： | 2001年12月4日 |
Preparation of in Vivo Degradable Material Used in Bone Fixation |
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| Shi Xiaolin,Xie Huaiqin.Preparation of in Vivo Degradable Material Used in Bone Fixation[J].Journal of Beijing University of Aeronautics and Astronautics,2003,29(2):144-146. | |
| Authors: | Shi Xiaolin Xie Huaiqin |
| Institution: | 1. School of Material Science and Enginerring,Harbin Institute of Technology; 2. Institute Chemistry and Chemical Engineering, Heilongjiang University |
| Abstract: | To develop a kind of material with moderale strength and flexibility for bone fixation. First a series of product polymeric on chain reaction was obtained between poly D,L lactide and poly several lactore. Then to detect change regulation which tensile strength and degrading properties of product polymeric following extending chain agent and extending chain reaction condition, extending chain agent was selected and the best technology was formulated. With the above method, the polymeric of bone fixation was made, which is harmless to human body.The tensile strength of this product polymeric is 24.47 MPa, and its breaking elengation ratio is 1091%, to degrade it need six months. |
| Keywords: | chain extendors degradation polycaprolactone poly D L lactide |
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