用国产装置进行的空间蛋白质结晶实验

使用国内研制的管式汽相扩散结晶装置，在我国返回式卫星上，成功地完成了两次空间蛋白质晶体生长实验，１０种不同种类的蛋白质配制的４８个样品在空间的出晶率分别达５２％和８０％，其中少数蛋白质生长出了较高质量的蛋白质晶体．结果表明，空间的微重力环境利于改善蛋白质晶体的生长，而且在结晶条件优化足够好的条件下，在空间里能生长出比地面晶体尺寸较大、形态较好和内部有序性较高的蛋白质晶体．本文还就微重力对蛋白质晶体生长的具体作用及其开发利用做了讨论．

SPACE CRYSTAL GROWTH OF PROTEINS WITH DOMESTIC FACILITY

The cytstal growth of proteins and other biomacromolecules is an important study in space science'Using tube-like vapour diffusion apparatus made in China,two missions of protein crystallization have been carried out on Chinese re-entry satellites.52% and 80% of 48 samples prepared by 10 different kinds of proteins yielded crystals in the two space experiments respectively,and among them,a few of the proteins preduced better-quality Crystals.The results of the two missions show that the microgravity environment in space benefits improvement of protein crystal growth, and in the case with good enough optimized crystallization conditions,the space-grown protein crystals have larger size,better morphology and higher intend order than the Earth-grown crystals of the same protein.The effect of microgravity on protein crystal growth and its exploitation are also discussed in the paper.