Decrease of contractile properties and transversal stiffness of single fibers in human soleus after 7-day “dry” immersion |
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| Authors: | IV Ogneva EV Ponomareva NL Kartashkina EG Altaeva NM Fokina VA Kurushin IB Kozlovskaya BS Shenkman |
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| Institution: | 1. Secretaría de Estado de Medio Ambiente, MAGRAMA, Plaza S. Juan de la Cruz, 28071 Madrid, Spain;2. Estación Espacial SEAS Canarias, ULPGC, 35017 Las Palmas de Gran Canaria, Canary Islands, Spain;3. Departamento de Biología, ULPGC, 35017 Las Palmas de Gran Canaria, Canary Islands, Spain;4. Departamento de Ingeniería Civil, ULPGC, 35017 Las Palmas de Gran Canaria, Canary Islands, Spain;1. Departamento de Ciencias de la Tierra, Facultad de Ciencias Experimentales, Campus de El Carmen, Universidad de Huelva, Avda. 3 de marzo, s/n, 21071 Huelva, Spain;2. Department of Geosciences, Faculty of Sciences & Information Technology, Universiti Teknologi PETRONAS (UTP), 32610 Bandar Seri Iskandar (Tronoh), Perak Darul Ridzuan, Malaysia;3. Facultad de Ciencias Marinas, Universidad Autónoma de Baja California, Ensenada, BC 22800, Mexico;4. Department of Geosciences, Williams College, Williamstown, MA 01267, USA;5. Departamento de Geologia and Instituto Dom Luiz de Geociências, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal |
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| Abstract: | The simulation model of “dry” immersion was used to evaluate the effects of plantar mechanical stimulation (PMS) and high frequency electromyostimulation (EMS) on the mechanical properties of human soleus fibers under the conditions of gravitational unloading. We examined contractile properties of single fibers by means of tensometry, transversal stiffness of sarcolemma and different areas of the contractile apparatus by means of atomic force microscopy. It was shown that there is a reduction of transversal stiffness in single muscle fibers under hypogravitational conditions. Application of different countermeasures could compensate this effect. Meanwhile pneumostimulation and electro stimulation act in quite different way. Therefore, pneumostimulation seems to be more effective. The data obtained can be considered as the evidence of the fact that such countermeasures as PMS and electromyostimulation influence on muscle fibers in quite different ways and PMS efficiency is likely to be higher. On the basis of our experimental data on transverse stiffness of mechanotransductional nodes and the contractile apparatus, we can assume that support stimulation allows prevention of destructive processes in muscle fibers. Electrostimulation seems to stimulate contractile activity only without suppression of impairment of the fiber mechanical properties. |
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