Molecular alterations in tumorigenic human bronchial and breast epithelial cells induced by high LET radiation.

Carcinogenesis is a multi-stage process with sequence of genetic events governing the phenotypic expression of a series of transformation steps leading to the development of metastatic cancer. In the present study, immortalized human bronchial (BEP2D) and breast (MCF-10F) cells were irradiated with graded doses of either 150 keV/micrometer alpha particles or 1 GeV/nucleon 56Fe ions. Transformed cells developed through a series of successive steps before becoming tumorigenic in nude mice. Cell fusion studies indicated that radiation-induced tumorigenic phenotype in BEP2D cells could be completely suppressed by fusion with non-tumorigenic BEP2D cells. The differential expressions of known genes between tumorigenic bronchial and breast cells induced by alpha particles and their respective control cultures were compared using cDNA expression array. Among the 11 genes identified to be differentially expressed in BEP2D cells, three (DCC, DNA-PK and p21(CIP1)) were shown to be consistently down-regulated by 2 to 4 fold in all the 5 tumor cell lines examined. In contrast, their expressions in the fusion cell lines were comparable to control BEP2D cells. Similarly, expression levels of a series of genes were found to be altered in a step-wise manner among tumorigenic MCF-10F cells. The results are highly suggestive that functional alterations of these genes may be causally related to the carcinogenic process.     

光敏元件与光传感器的市场动态和发展

介绍了光敏元件与光传感器技术的发展及在国民经济和军事领域中的重要怍用；分析了国内外光电子产业的市场动态与发展趋势；论述了我国光电子产业面临的机遇和挑战。     

激光外差干涉仪光电信号处理方法及特点

叙述和分析了外差激光干涉光电信号处理主其特点，指出了它们各自的应用范围，同时介绍了一处新型的光电信号处理方法，它不仅使外差干涉仪用于动态测量，而且可以同时实现高分辩率测量 。     

k-ε-g紊流燃烧模型数值研究

本文对k-ε-g紊流燃烧模型中模型系数C_R,C_(g1),C_(g2)的选定和计算浓度脉动均方值g的不同方法进行数值研究。计算结果表明模型系数值的选定直接与化学反应速率有关,而其中C_R影响最大。g的计算虽然可有不同方法,而其中微分方程求解最佳。并用实验数据来验证计算结果。     

改进的次时间最优控制

本文在[1][2]基础上进一步探讨了次时间最优控制的改进问题,深入地阐明了次时间最优控制的某些特性后,提出了一个新的改进的设计方法。按照这种方法设计控制系统,不但实用而且可以大幅度提高次时间最优控制的最优性。并用实例比较了各种方法,证明了本文提出的方法的优越性。本文提出的方法应用于工程设计,对于提高系统的最优性是非常有效的。     

波导分支线定向耦合器计算方法

利用模匹配方法和网络理论分析计算了一种卫星天线系统中常用的波导分支线定向耦合器,计算结果与实验结果非常吻合。该方法为波导分支线定向耦合器提供一种有力的设计手段。它可直接用于设计Ku 波段通信卫星天线的波束形成网络,也可以用来设计各种耦合度的波导分支线定向耦合器。     

Optimal multiple level decision fusion with distributed sensors

A data fusion model consisting of several levels of parallel decision fusions is considered. Global optimization of such a model is discussed to obtain the fusion rules for overall optimal performance. The reliability analysis of the proposed model is carried out to establish its superiority over the existing parallel and serial fusion models     

Hill区域内基于推广的Poincar映射的低能逃逸/捕捉轨道(英文)

给出了Hill区域内基于推广的Poincar映射的低能逃逸轨道的计算。文中的推广的Poincar映射需要在相空间中选取两个(而非一个)与流相截的面,即将包含某个天平动点的截面通过轨道来映射到近拱点的通道面上的,在数值上通过总变差减小的Runge-Kutta方法来实现两个相面之间的映射。捕捉轨道则可由Hill三体模型的对称性直接导出。最后,关于Rhea的二维、三维的逃逸和捕捉轨道的仿真结果验证了该方法的精度和鲁棒性。     

浅谈发挥低年级学生学习英语的积极性

英语教学，特别是低年级英语教学既需要教师的积极性，更需要学生的积极性，二者缺一不可。要想发挥学生的学习积极性，首先应发挥英语自身的魅力，启发学生的积极性；其次，以情感促教学调动学生的积极性；再者，采取有效措施巩固学生的积极性。     

三维模型中关键特性标注和提取的实现

关键特性作为"少数重要"的产品信息,是保证产品质量和顾客满意度的重要因素,其指定和标识需要与三维模型相结合才具有更直观的意义,同时也方便对其进行更有效的管理.本文给出了关键特性的定义和分类,提出了三维模型中关键特性的标注方法,通过对UG进行二次开发,实现了关键特性的属性添加和信息提取,并通过某型导弹弹头舱段壳体零件进行了验证.