Skylab experiment results: hematology studies

These studies were designed and coordinated to evaluate specific aspects of man's immunologic and hematologic systems which might be altered by or respond to the space flight environment. The biochemical functions investigated included cytogenetic damage to blood cells, immune resistance to disease, regulation of plasma and red cell volumes, metabolic processes of the red blood cell, and physical chemical aspects of red blood cell functions. Only minor changes were observed in the functional capacity of erythrocytes as determined by measuring the concentrations of selected intracellular enzymes and metabolites. Tests of red cell osmotic regulation indicated some elevation in the activity of the metabolic dependent Na-K pump, with no significant alterations in the cellular Na and K concentrations or osmotic fragility. A transient shift in red cell specific-gravity profile was observed on recovery, possibly related to changes in cellular water content. Measurements of hemoconcentration (hematocrit, hemoglobin concentration, red cell count) indicated significant fluctuations postflight, reflecting observed changes in red cell mass and plasma volume. There was no apparent reticulocytosis during the 18 days following the first manned Skylab mission in spite of a significant loss in red cell mass. However, the reticulocyte count and index did increase significantly 5 to 7 days after completion of the second, longer duration, flight. There were no significant changes in either the while blood cell count or differential. However, the capacity of lymphocytes to respond to an in vitro mitogenic challenge was repressed postflight, and appeared to be related to mission duration. The cause of this repression is unknown at this time. Only minor differences were observed in plasma protein patterns. In the second mission there were changes in the proteins involved in the coagulation process which suggested a hypercoagulative condition.     

Linear FM Signal Formats for Beacon and Communication Systems

This paper examines the capabilities of the class of linear FM spread-spectrum signals within the context of potential communications systems usage in order to establish some performance criteria and bounds that permit comparison with other spread-spectrum formats. A systematic basis is provided for parameter selection for this class of signals by examining the interaction a mong the frequency-modulation indices, time-bandwidth product, and cross-talk criteria that determine the number of effective linear FM signals (or channels) that can be used within the constraints of a bounded time-frequency region. A general expression is derived relating N, the number of useful signals, R2, a cross-talk parameter, ToWo, the mean time-bandwidth product, and ?max and ?min, the maximum and minimum FM rates of the signal set. Canonic signal processor structures are described for ensembles of linear FM signals that have either constant duration or constant bandwidth. It is then shown that the signal modulation format can be modified in accordance with classical paired-echo theory to expand the utility of this class of signals in both synchronous and nonsynchronous operations to yield the equivalent of time-division and code multiplexing. Possible applications for this signal format are discussed.     

Theoretical consideration of the chemical pathways for radiation-induced strand breaks.

A theoretical approach to the understanding of the biochemical mechanisms of indirect action of ionizing radiation on SV40 DNA in aqueous solution is presented. The extent of OH attack on the sugar moiety and bases has been calculated. A realistic model for the DNA (in B form) based on available X-ray diffraction data is used and specific reaction sites for the OH radicals are obtained. A Monte Carlo scheme is used to follow the diffusion and reaction of the OH radicals. Effects of track structure have been considered and the single strand break D37 values for 14 MeV electrons (low-LET) and 670 MeV/u and 40 MeV/u neon particles are presented. Calculated results are in agreement with available experimental data. It has been found that regardless of the qualities of radiation, 80% of the OH attack on DNA is on the bases and 20% is on the deoxyribose. From probability considerations only, it appears that the number of double strand breaks varies linearly with dose.     

Crystallization of metal alloys in microgravity and uniform compression conditions

This is an analysis of the experimental results to study the metastable phase formation while crystallization of binary metal melts in microgravity and quasi-isostatic (uniform) compression takes place. The alloy system PbSn serves as an illustration     

Droplet vaporization in supercritical pressure environments

For most liquid-fueled combustion systems the behavior of the fuel as it is introduced to the combustion zone, often by spray injection, will have a significant impact on combustion. The subsequent combustion may be affected to a considerable degree by the initial spread of the liquid, break-up of larger fuel sheets and droplets into droplets of various sizes, droplet vaporization, and diffusion of gaseous fuel. Among the many factors which affect spray break-up and droplet vaporization are the environmental conditions into which the spray is introduced. For both diesel engines and rockets the environment pressure and temperature may be above the critical pressure and temperature of the injected fuel. In a compression-ignition internal combustion engine, the environment consists primarily of air, at pressures from 20 to 100 atmospheres and temperatures ranging from 900 to 1500 K. Even higher pressures are encountered in turbocharged diesels. A typical diesel reference fuel, dodecane, has a thermodynamic critical pressure of about 17 atmospheres, and a critical temperature of 600 K. Fuel is injected into a diesel engine environment in which ambient pressures exceed the critical pressure. While droplet temperatures are subcritical at first, they may rise to the critical temperature or higher.This paper will survey current understanding of supercritical pressure droplet vaporization. Specifically, the topics covered will include: liquid phase behavior; vapor phase behavior; thermodynamic and transport properties; droplet distribution and break-up; micro-explosions; and effects of microgravity.     

A new calibration of the semi-empirical photometric theory for Halley and other comets

A massive new body of data, comprised of spectrophotometry of 17 comets by Newburn and Spinrad, has now become available for calibration of the basic theory, the Semi-Empirical Photometric Theory, used for modelling of Comet Halley. A redetermination of the constant $\text{R}$ and the function δ has been made, and no change is needed. Improved mixing ratios given as a function of heliocentric distance also permit an improvement in the constants of the visual photometric model presented at COSPAR XXIV. A new light curve for Halley and a lower dust to gas ratio prove to make roughly compensating changes in dust densities.     

Mass spectrometric measurements of stratospheric ions

Recent in situ measurements with balloon borne quadrupole mass spectrometers, between 20 and 45 km altitude, are reviewed and discussed.The major stratospheric positive ions observed are proton hydrates [H⁺(H₂O)_n] and non proton hydrates of the form H⁺X_m(H₂O)₂. The data analysis allows a derivation of the vertical mixing ratio profile of X (most probably CH₃CN), which is compared with recent model calculations. From negative ion composition data, showing the presence of NO₃^? and HSO₄^? cluster ions, the density of sulfuric acid in the stratosphere is deduced. The implications of these findings on our understanding of the sulfur chemistry is briefly treated.Finally some other aspects such as contamination, cluster break up and the use of stratospheric ion mass spectra for determination of thermochemical data and other minor constituents are discussed.     

An Analytical Expression for Correlation Accuracy

An analytical closed-form expression for the uncertainty in aligning two images is derived as a function of image area, data fidelity, scene correlation length, limiting sensor resolution length, and degree of geometrical distortion between the two images.     

Effects due to an artificial earth satellite in rapid motion through the ionosphere or the interplanetary medium

Conclusion In this paper we have been concerned with the results of theoretical calculations of the interaction between a fast moving body and a tenuous plasma. Particular attention was paid to the case where the velocity of the body is much smaller than the velocity of neutral particles and ions, while the dimensions of the body are sufficiently large in comparison with the Debye radius. Such conditions are realized during the motion of artificial satellites or space rockets through the ionosphere, or through the interplanetary medium in the immediate neighborhood of the earth. Although this case has, on the whole, been investigated quite extensively, there are still a number of problems which require further analysis. Firstly, it is necessary to take into account the effect of the electric field on the motion of ions in the near zone at the rear of the body. Another important problem is that of magnetic disturbances. In the case of scattering of radio waves by the trail of the body, it would be interesting indeed to know the increase in the effective cross-section in the resonance region in which 0. A number of other research problems which arise in the analysis of phenomena in the neighborhood of a moving body have been noted in the Introduction.In the lower layers of the ionosphere it is important to allow for the fact that the dimensions of the body are comparable with the mean free path. Under these conditions there is the further interesting problem of the heating and additional ionization of the plasma, the disintegration of the surface, and the emission of waves. At large distances from the surface of the earth, the dimensions of the body may become comparable with the Debye radius, and the velocity of the body in the given region may become smaller than the thermal velocity of the particles. The character of the various disturbances introduced by the body under these conditions will also require a special investigation.Thus, the interaction of a moving body with plasma leads to special and exceptionally varied effects. Disturbances due to the body are very considerable, so that the physical state of the region surrounding the body is very different from the state of the undisturbed medium.The above results indicate that the phenomena in the neighborhood of satellites and space rockets in the ionosphere, or the interplanetary medium, must be taken into account, in the processing of experimental data when it is required to deduce information about the state of the undisturbed medium. This is particularly important in the analysis of the results of measurements obtained with various types of probes. Considerable errors may be introduced if these effects are not allowed for.Further extensive experimental and theoretical studies of the structure of the disturbed region in the neighborhood of moving bodies in plasma are clearly necessary. Such investigations will, in particular, lead to the development of the most effective methods of studying the properties of the media through which satellites and space rockets travel.Translated from the Russian: Ob effektah vyzyvaemyh iskusstvennym sputnikom bystro dviimsja v ionosfere ili meplanetnoj srede (Uspehi fizieskih nauk 79, 23–80) by Express Translation Service.     

Microprocessor-Controlled Communications in an Advanced Instrument Landing System

The application of 4-bit microprocessors to the communication of the control and status signals found in an advanced aircraft instrument landing system is presented. The advantages as well as some of the peculiarities of such an approach are described. Among the benefits, one must include the possibility of a very convenient and understandable human interface.