俯仰运动矩形贮箱中液体的非线性晃动

首先针对俯仰运动贮箱中液体的晃动提出了变分原理和新一类Lagrange函数，以此为基础可以解析方式来研究俯仰运动贮箱中液体有限幅值晃动。以无挡板开口二维、刚性短形贮箱为例，研究了其中液体的有限幅值晃动。单就液体波动幅值而言，在一定激励频率范围内，理论计算值与实验结果具有很好的一致性。     

引入摩擦元模拟桩土共同作用

要桩侧和桩周土界面引入摩擦元，能较好地模拟桩土共同作用工作状态，既考虑了剪力的传递，又考虑了相对位移，通过实例计算分析得到了一些令人满意的结果。     

Simulated microgravity induce apoptosis and down-regulation of erythropoietin receptor of UT-7/EPO cells

Hematopoietic progenitor cell proliferation can be alternated on either spaceflight or under simulated microgravity experiments on the ground; however, the underlying mechanism remains largely unknown. In the present study, we have demonstrated that exposure of human erythropoietin (EPO)-dependent leukemia cell line UT-7/EPO cells to conditions of simulated microgravity with a rotary culture instrument significantly inhibited the cellular proliferation rate. Adding higher concentrations of EPO to the culture medium failed to improve the inhibitory status. Cell apoptosis was detected by fluorescence staining of cell nuclei and a flow cytometry assay using Annexin V/PI double staining. This microgravity-induced apoptosis in UT-7/EPO cells could be blocked by a pancaspase inhibitor Z-VAD-FMK. Immunoblotting demonstrated that rotary culture resulted in a reduction of the expression of Bcl-xL, an anti-apoptotic protein, and the cleavage of caspase-3. Furthermore, rotary culture reduced surface localization and protein content, as well as the mRNA expression of erythropoietin receptor (EPOR) of UT-7/EPO. Take together, the findings indicated that simulated microgravity may induce mitochondrial related apoptosis of UT-7/EPO cell through depressing the EPO–EPOR pathway.     

大型弹簧电镀锌工艺优化

采用扫描电镜(SEM)研究了发蓝、超声波酸洗前处理工艺对大型弹簧零件表面残余氧化皮的去除效果以及这两种前处理工艺对镀锌层的结合力与抗腐蚀性能的影响。结果表明,采用适当的发蓝、超声波酸洗等前处理工艺,能够有效去除零件表面顽固的残余氧化皮,较大幅度地提高镀锌层与金属基体的结合力,并提高镀锌层的抗腐蚀性能。     

高硬度薄壁筒形件数控车加工工艺

以典型零件加工为例,通过探讨高硬度薄壁零件在数控车床加工中存在的易变形、零件尺寸及表面粗糙度不易保证、断续切削时刀具易破损等技术问题,对加工难点进行分析,给出了工艺路线和加工方案,通过优化、完善夹具设计、加工程序和切削参数,使用新型刀具,并打破硬态切削的一些常规做法,从而有效解决高硬度薄壁类零件的车削加工难题。     

某型飞机进气道斜板加载测控系统的研究

在飞机进气道斜板位置控制系统的地面试验过程中，需要模拟实际飞行状态中斜板所受到的气动载荷谱。     

Upregulation of erythropoietin receptor in UT-7/EPO cells inhibits simulated microgravity-induced cell apoptosis

Hematopoietic progenitor cell proliferation can be altered in either spaceflight or under simulated microgravity experiments on the ground, however, the underlying mechanism remains unknown. Our previous study showed that exposure of the human erythropoietin (EPO)-dependent leukemia cell line UT-7/EPO to conditions of simulated microgravity significantly inhibited the cellular proliferation rate and induced cell apoptosis. We postulated that the downregulation of the erythropoietin receptor (EPOR) expression in UT-7/EPO cells under simulated microgravity may be a possible reason for microgravity triggered apoptosis. In this paper, a human EPOR gene was transferred into UT-7/EPO cells and the resulting expression of EPOR on the surface of UT-7/EPO cells increased approximately 61% (p < 0.05) as selected by the antibiotic G418. It was also shown through cytometry assays and morphological observations that microgravity-induced apoptosis markedly decreased in these UT-7/EPO–EPOR cells. Thus, we concluded that upregulation of EPOR in UT-7/EPO cells could inhibit the simulated microgravity-induced cell apoptosis in this EPO dependent cell line.     

基于B/S架构的设备全寿命周期管理系统技术研究

研究了基于B/S架构(Browser/Server结构)的设备全寿命周期管理系统相关技术,论述了构成设备全寿命周期管理系统的架构设计与模块划分。将网络、多媒体、数据库等技术通过计算机软件系统开发的理论、技术和方法建立起的B/S架构应用于航空聚合物基复合材料厂的设备管理。该系统可使相关基础管理工作以信息化手段简化、固化与落实。     

Kalman filtering for GPS/magnetometer integrated navigation system

This paper investigated the data processing method for a GPS/IMU/magnetometer integrated system with Kalman filtering (KF). As a result of GPS/IMU/magnetometer land vehicle system, dead-reckoning of magnetometer and accelerometer integrated subsystem bridged very well the GPS signal outage due to the trees on the two sides of the road. Both differential GPS data processing method and the carrier-phase method with magnetometers’ outputs for predicting the car position, velocity, and acceleration (PVA) are presented. The results from DGPS with Kinematical Positioning (KINPOS) software shown that the averages of the north, east, and down direction standard deviation (short for “std”) are 0.014, 0.010, and 0.018 m, respectively. The std of velocities and accelerations derived by the position and velocity differentiation are 10, 7, 13 mm/s, 7, 5, 9 mm/s², respectively. This method for getting velocities and accelerations requires higher accurate position coordinates. But the position accuracy has frequently been degraded in this case when the car drove under the trees or other similar kinematical environments. That caused the larger velocity and acceleration errors. While the results from the carrier-phase method are std of the velocities = 2.1 mm/s, 1.3 mm/s, 3.7 mm/s in north, east, down, and std of the accelerations = 1.5 mm/s², 0.9 mm/s², 2.3 mm/s² for the static test period; as compared with KINPOS software results, std of the velocity difference between the carrier-phase method and the DGPS method = 7 mm/s, 6.9 mm/s, 9.7 mm/s in north, east, down direction, and std of acceleration difference = 5.0 mm/s², 4.5 mm/s², 7.5 mm/s² in north, east, down direction for the kinematical test period. Obviously, errors come from both the carrier-phase method and DGPS velocity and acceleration results derived directly by the position differentiation. In addition, better accuracy of positions than that before KF has been got by means of velocities and accelerations derived by the carrier-phase method after KF.     

A review of 9-year performance and operation of the MOPITT instrument

The MOPITT (Measurements of Pollution in the Troposphere) instrument has provided more than nine years of global carbon monoxide (CO) measurements on a continuous basis since its launch aboard the Terra Spacecraft on December 18th, 1999. This paper gives an overview of the core sub-system performance and major issues of the in-flight instrument over the mission period. Some of the instrument anomalies are also discussed. The major successes are: (1) the concept of using a combination of correlation systems such as Length Modulated Cells (LMCs) and Pressure Modulated Cells (PMCs) to retrieve CO profiles in the troposphere; (2) the redundant design in the instrumentation which was crucial for coping with unexpected in-flight anomalies and for continuing the mission in the case of component failure; (3) the thermal environment on orbit that is so stable that some calibration procedures are not necessary; and (4) the recent production of CO total column retrieved from the MOPITT 2.3 μm channel.