Microgravity effects on "postural" muscle activity patterns.

Changes in neuromuscular activation patterns associated with movements made in microgravity can contribute to muscular atrophy. Using EMG to monitor "postural" muscles, it was found that free floating arm flexions made in microgravity were not always preceded by neuromuscular activation patterns normally observed during movements made in unit gravity. Additionally, manipulation of foot sensory input during microgravity arm flexion impacted upon anticipatory postural muscle activation.     

Development of plant protoplasts during the IML-1 mission.

During the 8 day IML-1 mission, regeneration of cell walls and cell divisions in rapeseed protoplasts were studied using the Biorack microscope onboard the Space Shuttle "Discovery". Samples from microgravity and 1g protoplast cultures were loaded on microscope slides. Visual microscopic observations were reported by the payload specialist Roberta Bondar, by down-link video transmission and by use of a microscope camera. Protoplasts grown under microgravity conditions do regenerate cell walls but to a lesser extent than under 1g. Cell divisions are delayed under microgravity. Few cell aggregates with maximum 4-6 cells per aggregate are formed under microgravity conditions, indicating that microgravity may have a profound influence on plant cell differentiation.     

Wind asymmetries in massive stars

We are in the process of surveying the linear polarization in luminous, early-type stars. We here report on new observations of the B [e] stars S 18 and R 50, and of the Luminous Blue Variables HR Car, R 143, and HD 160529. Together with previously published data, these observations provide clear evidence for the presence of intrinsic polarization in 1 B[e] star (HD 34664) and in 5 LBVs ( Car, P Cyg, R 127, AG Car, and HR Car). The data indicate that anisotropic stellar winds are a common occurrence among massive stars in these particular evolutionary stages. For such stars, mass-loss rates estimated using the assumption of a spherical, homogeneous and stationary outflow may be in error.     

IMF connection for energetic protons observed at Ulysses via mid-latitude solar wind rarefaction regions

As Ulysses moved inward and southward from mid-1992 to early 1994 we noticed the occasional occurrence of inter-events, lasting about 10 days and falling between the recurrent events, observed at proton energies of 0.48–97 MeV, associated with Corotating Interaction Regions (CIR). These inter-events were present for several sequences of two or more solar rotations at intensity levels around 1% of those of the neighbouring main events. When we compared the Ulysses events with those measured on IMP-8 at 1 AU we saw that the inter-events appeared at Ulysses after the extended emission (>10 days) of large fluxes of solar protons of the same energy that lasted at least one solar rotation at 1 AU. The inter-events fell completely within the rarefaction regions (dv/dt<0) of the recurrent solar wind streams. The interplanetary magnetic field (IMF) lines in the rarefactions map back to the narrow range of longitudes at the Sun which mark the eastern edge of the source region of the high speed stream. Thus the inter-events are propagating at mid-latitudes to Ulysses along field lines free from stream-stream interactions. They are seen in the 0.39–1.28 MeV/nucleon He, which exhibit a faster decay, but almost never in the 38–53 keV electrons. We show that the inter-events are unlikely to be accelerated by reverse shocks associated with the CIRs and that they are more likely to be accelerated by sequences of solar events and transported along the IMF in the rarefactions of the solar wind streams.     

Biochemical constraints for survival under Martian conditions.

A wide variety of terrestrial organisms, the so-called "anhydrobiotes," has learned to survive in a state of extreme dehydration in dry environments. Strategies for survival include the accumulation of certain polyols and nonreducing saccharides, which help to prevent damage to membranes and proteins, but at low water partial pressure DNA is also progressively damaged by various lesions, including strand breaks and cross-linking to proteins. These lesions, if they are not too numerous, can be repaired before the first replication step after rehydration, but long-term exposure to dry conditions finally diminishes the chances of survival as these lesions accumulate. If an organism has no chance to repair the accumulated DNA damage during intermittent periods of active life, survival will not exceed a few decades. The restriction of survival by dryness-induced DNA lesions is corroborated by new data on conidia of Aspergillus and the free plasmid pBR 322. Our results will be discussed with respect to the chance of finding dormant life or biochemical fossils on the surface of Mars.     

Leg venous hemodynamics and leg volumes during a 42 day -6 degrees head-down bedrest

Seven healthy subjects were submitted to a 42-day head down bedrest, where leg venous compliance (venous distensibity index VDI) and leg volumes were assessed by mercury strain gauge plethysmography with venous occlusion and optoelectronic plethysmography, respectively. Plethysmographic and volometric measurements were made, before, during (at days 1, 4, 7, 14, 21, 26, 34 and 41), and after bedrest (days 1, 4, 7, 11 and 30 of the recovery period). Results showed a continuous decrease in leg volumes throughout bedrest, when VDI increased until day 26 of bedrest, and then decreased afterwards. The recovery period was characterized by a rapid return of VDI to prebedrest levels while leg volumes progressively normalised. These results showed that leg venous compliance changes are not always dependant upon skeletal muscle changes, and that factors other than size of muscle compartment are able to determine increases in leg venous compliance during long-term bedrest.     

On the correlation between individual biochemical parameters of human blood serum following space flight and their basal values

The article presents data concerning the osmolality and concentration of electrolytes and hormones regulating their balance for blood serum of 223 cosmonauts and astronauts. The obtained results allow us to judge the constancy of physicochemical parameters for the blood serum of healthy individuals and how they react to extreme conditions of space flight. The parameters used for evaluation included not just absolute values for the examined indices, but also how they responded to space flight, the dependence on baseline values and the interrelationship between ions. These data are important to predict the effect of exposure to extreme conditions and point to what extent the effect depends on the characteristics of the individual.     

Cosmic ray modulation in the 3-D heliosphere

The basic physical processes that lead to the long-term modulation of cosmic rays by the solar wind have been known for many years. However our knowledge of the structure of the heliosphere, which determines which processes are most important for the modulation, and of the variation of this structure with time and solar activity level is still incomplete. Study of the modulation provides a tool for probing the scale and structure of the heliosphere. While the Pioneer and Voyager spacecraft are surveying the radial structure and extent of the heliosphere at modest heliographic latitudes, theUlysses mission is the first to undertake a nearly complete scan of the latitudinal structure of the modulated cosmic ray intensity in the inner heliosphere (R<5.4 AU).Ulysses will reach latitudes of 80°S in September 1994 and 80°N in July 1995 during the approach to minimum activity in the 11 year solar cycle. We present a first report of measurements extending to latitudes of 52°S, which show surprisingly little latitudinal effect in the modulated intensities and suggest that at this time modulation in the inner heliosphere may be much more spherically symmetric than had generally been believed based upon models and previous observations.     

Tracking multiple objects with particle filtering

We address the problem of multitarget tracking (MTT) encountered in many situations in signal or image processing. We consider stochastic dynamic systems detected by observation processes. The difficulty lies in the fact that the estimation of the states requires the assignment of the observations to the multiple targets. We propose an extension of the classical particle filter where the stochastic vector of assignment is estimated by a Gibbs sampler. This algorithm is used to estimate the trajectories of multiple targets from their noisy bearings, thus showing its ability to solve the data association problem. Moreover this algorithm is easily extended to multireceiver observations where the receivers can produce measurements of various nature with different frequencies.     

Comparison of two measurement fusion methods forKalman-filter-based multisensor data fusion

Currently there exist two commonly used measurement fusion methods for Kalman-filter-based multisensor data fusion. The first (Method I) simply merges the multisensor data through the observation vector of the Kalman filter, whereas the second (Method II) combines the multisensor data based on a minimum-mean-square-error criterion. This paper, based on an analysis of the fused state estimate covariances of the two measurement fusion methods, shows that the two measurement fusion methods are functionally equivalent if the sensors used for data fusion, with different and independent noise characteristics, have identical measurement matrices. Also presented are simulation results on state estimation using the two measurement fusion methods, followed by the analysis of the computational advantages of each method