Track structure in biological models.

High-energy heavy ions in the galactic cosmic radiation (HZE particles) may pose a special risk during long term manned space flights outside the sheltering confines of the earth's geomagnetic field. These particles are highly ionizing, and they and their nuclear secondaries can penetrate many centimeters of body tissue. The three dimensional patterns of ionizations they create as they lose energy are referred to as their track structure. Several models of biological action on mammalian cells attempt to treat track structure or related quantities in their formulation. The methods by which they do this are reviewed. The proximity function is introduced in connection with the theory of Dual Radiation Action (DRA). The ion-gamma kill (IGK) model introduces the radial energy-density distribution, which is a smooth function characterizing both the magnitude and extension of a charged particle track. The lethal, potentially lethal (LPL) model introduces lambda, the mean distance between relevant ion clusters or biochemical species along the track. Since very localized energy depositions (within approximately 10 nm) are emphasized, the proximity function as defined in the DRA model is not of utility in characterizing track structure in the LPL formulation.     

三维四向编织复合材料弹性模量数值预报

 对三维四向编织复合材料的参数化建模技术进行了研究,提出了一种"米"字型枝状体胞的计算模型,较为真实地模拟了该材料的细观结构;在此基础上讨论了相应的边界条件和约束条件并应用有限元方法计算了该材料的纵向、横向弹性模量.通过与实验结果的对比可见,计算结果的预报精度较好.     

Nostoc sphaeroides Kützing,an excellent candidate producer for CELSS

Some phytoplankton can be regarded as possible candidates in the establishment of Controlled Ecological Life Support System (CELSS) for some intrinsic characteristics, the first characteristic is that they should grow rapidly, secondly, they should be able to endure some stress factors and develop some corresponding adaptive strategies; also it is very important that they could provide food rich in nutritious protein and vitamins for the crew; the last but not the least is they can also fulfill the other main functions of CELSS, including supplying oxygen, removing carbon dioxide and recycling the metabolic waste. According to these characteristics, Nostoc sphaeroides, a potential healthy food in China, was selected as the potential producer in CELSS. It was found that the oxygen average evolution rate of this algae is about 150 μmol O₂ mg⁻¹ h⁻¹, and the size of them are ranged from 2 to 20 mm. Also it can be cultured with high population density, which indicated that the potential productivity of Nostoc sphaeroides is higher than other algae in limited volume. We measured the nutrient contents of the cyanobacterium and concluded it was a good food for the crew. Based on above advantages, Nostoc sphaeroides was assumed to a suitable phytoplankton for the establishment of Controlled Ecological Life Support System. We plan to develop suitable bioreactor with the cyanobacterium for supplying oxygen and food in future space missions.     

Studies on precellular evolution: the encapsulation of polyribonucleotides by liposomes.

Liposomes are 5 to 50 micron vesicles with an internal aqueous environment, whose amphiphilic lipidic components self-assemble into systems with at least one double-layered membrane. Liposomes have been suggested as possible models of precellular systems formed in the early Archean Earth from lipids of non-enzymatic origin. Since it is generally accepted that RNA molecules preceded double-stranded DNA molecules as genetic material, we have studied the encapsulation of polyribonucleotides within liposomes made from dipalmitoyl phosphatidylcholine, and from egg yolk phosphatidylcholine to which cholesterol was added in some cases. The liposomes were prepared under anoxic conditions following the reverse phase evaporation method described by Szoka and Papahadjopoulos. Quantitative determinations show that approximately 50% of the available lipids form liposomes, and that up to 5% of the polyribonucleotides can be entrapped by them. We have also studied the encapsulation of polyribonucleotides in the presence of 1) urea and cyanamide, two non-electrolytes that have been used as prebiotic condensing agents, and 2) of Zn++ and Pb++, two cations employed in the non-enzymatic template-directed synthesis of polyribonucleotides from activated nucleotides.     

一种新的流媒体批处理补丁缓存算法

在分布式流媒体分送系统中,一个关键的问题就是如何降低骨干网络带宽的消耗.通过在网络的边缘部署代理服务器,由代理负责响应本地客户的请求并转交从服务器来的媒体数据流.将服务器的批处理补丁调度技术与代理服务器分段缓存策略有效地结合起来,提出了批处理补丁预先缓存算法(BPP).根据当前客户请求到达的分布情况,代理服务器提前分配相应的缓存空间,对正在进行的组播多媒体数据流实行分段缓存,使后续到达的客户请求能够共享代理服务器中缓存的数据段.理论分析及实验结果表明了该算法能够明显降低骨干网络带宽的消耗,并对客户请求到达速率的变化具有很好的适应性.     

Search for methane on Mars: Observations,interpretation and future work

The detection of methane on Mars has been reported by three different teams in 2004. Two of them used ground-based high-resolution spectroscopy in the near infrared range. The third one used the Planetary Fourier Spectrometer aboard Mars Express. Among the data sets, two of them reported a mean CH₄ mixing ratio of 10 ppb. However, these are marginal detections, which should be considered as tentative. The third (ground-based) data set, unpublished so far, seems to show evidence for strong localized sources of CH₄, corresponding to mixing ratios as high as 250 ppb in some cases. However, the high values reported in 2003 were not confirmed by subsequent observations performed by the PFS instrument in 2004. In the absence of a refereed publication, it is difficult to judge if the high values are indeed correct. Assuming that they are, the lack of their confirmation by the PFS could have several explanations, including, among others, localized transient vents, or time variations in the methane destruction rate. A biogenic source was first suggested for the martian methane. However, later studies showed that an abiotic source such as hydrogeology can be just as effective. Further dedicated observations are obviously needed to firm up the detection and distribution of methane on Mars.     

Geomagnetically trapped heavy ions resulting from the anomalous cosmic rays

Blake and Freisen painted out that if the anomalous cosmic rays are only singly charged they can penetrate deeply into the Earth's magnetosphere well below the cutoff for stripped ions. Ions which reach low altitude can be stripped by the residual atmosphere and become stably trapped. An experiment has been developed which will be able to detect the intensities of such stably trapped heavy ions as a function of magnetospheric position. In anticipation of the flight of this experiment, the fluxes and spectra of the trapped heavy ions have been calculated based upon the anomalous component observed in the IPM.     

The effects of simulated microgravity on cultured chicken embryonic chondrocytes.

Using the cultured chicken embryonic chondrocytes as a model, the effects of simulated microgravity on the microtubular system of the cellular skeleton, extracellular matrix, alkaline phosphatase activity, intracellular free calcium concentration and mitochondrial ATP synthase activity with its oligomycin inhibition rate were studied with a clinostat. The microtubular content was measured by a flow cytometer. The decrease of microtubular content showed the impairment of the cellular skeleton system. Observation on the extracellular matrix by the scanning electron microscopy showed that it decreased significantly after rotating, and the fibers in the extracellular matrix were more tiny and disorderly than that of the control group. It can be concluded that the simulated microgravity can affect the secreting and assembly of the extracellular matrix. In contrast to the control, there was a time course decrease in alkaline phosphatase activity of chondrocytes, a marker of matrix mineralization. Meanwhile a significant drop in the intracellular calcium concentration happened at the beginning of rotation. These results indicate that simulated microgravity can suppress matrix calcification of cultured chondrocytes, and intracellular free calcium may be involved in the regulation of matrix calcification as the second signal transmitter. No significant changes happened in the mitochondrial ATP synthase activity and its oligomycin inhibition rate. Perhaps the energy metabolism wasn't affected by the simulated microgravity. The possible mechanisms about them were discussed.     

基于经验模态分解的地球同步轨道高能电子通量预报

在磁暴恢复相期间,大量相对论(高能)电子从磁层的外辐射带渗透到地球同步轨道区.其中> 2 MeV的高能电子能够穿透卫星表面并聚积在材料内部,导致卫星无法正常运行或完全损坏.磁暴期间的高能电子通量变化的非平稳与非线性特征十分明显.通过实验发现,经验模态分解法能够极大地降低高能电子通量非平稳性问题造成的预报影响.以2008-2009年的数据作为训练集,2010-2013年数据作为测试集.结果表明:2010-2013年的预报率约为0.84;在太阳活动较为复杂的2013年,预报率达到0.81.引入经验模态分解后预报效率得到显著提高.     

Effect of clinostat rotation on differentiation of embryonic bone in vitro.

We have investigated the effect of changes in the gravity vector on osteoblast behaviour, using the clinostat set at 8 rpm. Two sources of osteoblasts were used: secondary cultures of fetal rat bone cells, and the rat osteosarcoma line 17/2.8 (ROS). Cell number was determined by incubation with 3-(4,dimethyl-2yl)-2,3 diphenyl) tetrazolium bromide (MTT) and measurement of optical density at 570 nm (OD). Alkaline phosphatase activity was detected by standard cytochemical methods. Dividing cells were localised by labelling dividing nuclei with Bromodeoxyuridine (BrdU), detected by immunofluorescence. Cell culture was initiated at densities between 1-4x10(4) cells ml-1. Growth rates in all cultures during the first 48 hours exposure to clinostat rotation were less than in stationary controls. After 3 days, ROS cell numbers were 35% lower, and calvarial cells 39% lower than their respective controls. Alkaline phosphatase activity in calvarial control cultures was uniformly present in characteristically polygonal cells, but after culture in the clinostat the enzyme was present sporadically, and the cells were cuboid. There was also no BrdU uptake in nuclei, but it was present in cell cytoplasms. We conclude that the clinostat decreases cell numbers and cell division. Both cell shape and the distribution of alkaline phosphatase activity in calvarial cell cultures were also affected. This implies that changes in the gravity vector can affect osteoblasts directly, without interaction with other cell types.     

一种基于压电驱动的火星岩石钻探器的研制

钻取采样是未来火星探测采样任务中获取星表岩石样本的一种有效方式。压电驱动的超声波钻取采样技术以压电陶瓷作为作动元件,对火星表面复杂环境具有一定的适应性。基于高频冲击钻进的工作原理,超声波钻探装置容易刺入火星表面坚硬的岩石。作为一种轻质小巧、低功耗的钻探器,超声波钻探器非常适合火星表面岩石的原位探测采样任务。本文借助仿真和试验手段验证了超声波钻探器的岩石钻进能力和钻探效率。超声波钻探器的研制可为未来火星表面岩石的钻探采样任务提供技术参考。     

Variations of quasi-electrostatic fields and ionosphere potential above lightning discharge at equatorial latitudes

Lightning discharges by thunderstorms cause generation of electromagnetic pulses and of quasi-electrostatic fields (QESF) in the atmosphere above, which occur in different time-scales. QESF penetrate into the mesosphere and the lower ionosphere where they are big enough to generate considerable electric charge transfer there and, in some cases, to cause red sprites. These processes may have an important contribution to the global atmospheric electric circuit. Significant transient variations of the ionospheric potential above the thunderstorm take place as well. QESF depend on the atmospheric conductivity and in the ionosphere they are affected also by its anisotropy determined by geomagnetic field orientation. QESF after a lightning discharge are investigated theoretically in this work in the case of equatorial latitudes (by horizontal geomagnetic field), where thunderstorms are important contributors to the global circuit. Results for DC electric fields in the lower equatorial ionosphere above a thundercloud obtained by earlier models demonstrate some specific features of the spatial distribution of these fields, which appear due to geomagnetic field orientation. Thus, the electric fields can be shifted by tens or more kilometers to east of the cloud charge region; also their horizontal scale is much bigger than in the case of middle latitudes. Here, a presence of similar specific features of quasi-electrostatic field distributions and ionospheric potential variations caused by a lightning stroke is studied. A situation when no secondary ionization is generated is considered. A model based on the Maxwell equations for potential electric fields is proposed. Computations of QESF in the middle atmosphere and of the ionospheric potential variations are provided as dependent on conductivity and its anisotropy in D-region. The obtained results for the ionosphere show that the electric fields in the equatorial lower ionosphere are comparable to these formed in the case of middle latitudes. However, their horizontal scales are much bigger and depend on conductivity profiles. Similar features are valid also for the ionospheric potential variations and for their horizontal scales.     

Solar cycles: A tutorial

The Sun is the nearest stellar and astrophysical laboratory, available for detailed studies in several fields of physics and astronomy. It is a sphere of hot gas with a complex and highly variable magnetic field which plays a very important role. The Sun shows an unprecedented wealth of phenomena that can be studied extensively and to the greatest detail, in a way we will never be in a position to study in other stars. Humans have studied the Sun for millennia and after the discovery of the telescope they realized that the Sun varies with time, i.e., solar activity is highly variable, in tune scales of millennia to seconds. The study of these variabilities helps us to understand how the Sun works and how it affects the interplanetary medium, Earth and the other planets. Solar power varies substantially and greatly affects the Earth and humans. Solar activity has several important periodicities, and quasi-periodicities. Knowledge of these periodicities helps us to forecast, to an extent, solar events that affect our planet. The most prominent periodicity of solar activity is the one of 11 years. The actual period is in fact 22 years because the magnetic field polarity of the Sun has to be taken into account. The Sun can be considered as a non-linear RLC electric circuit with a period of 22 years. The RLC equivalent circuit of the Sun is a van der Pol oscillator and such a model can explain many solar phenomena, including the variability of solar energy with time. Other quasi-periodicities such as the ones of 154 days, the 1.3, 1.7 to 2 years, etc., some of which might be harmonics of the 22 year cycle are also present in solar activity, and their study is very interesting and important since they affect the Earth and human activities. The period of 27 days related to solar rotation plays also a very important role in geophysical phenomena. It is noticeable that almost all periodicities are highly variable with time as wavelet analysis reveals. It is very important for humans to be in a position to forecast solar activity during the next hour, day, year, decade and century, because solar phenomena affect life on Earth and such predictions will help politicians and policy makers to better serve their countries and our planet.     

Peculiarities of the nighttime winter foF2 increase over Irkutsk

An analysis of properties and peculiarities of the nighttime winter foF2 increases (NWI) in the East Siberia is made on data of ionospheric station Irkutsk in the periods 1958–1992 and 2002–2009 and the empirical model of the F2 layer critical frequency under the geomagnetic quiet conditions deduced from these data (model Q-F2). It is revealed, that the NWI is the stable regularity of the quiet ionosphere over Irkutsk. The amplitude of the NWI (the difference between maximum and minimum foF2 values at night hours) is the greatest in December–January and nearly the same at low and middle solar activity. It is a peculiarity of the quiet ionosphere in the East Siberia. Maximum in night foF2 under quiet geomagnetic conditions is observed mainly after midnight (02-04 LT) and is shifted to predawn hours as solar activity increases. At low solar activity the quiet ionosphere at ∼02–04 LT shows the following properties: (a) the fluctuations of foF2 and hmF2 are in the reverse correlation but this dependence is weak; (b) very strong fluctuations of foF2 (|δfoF2| > 30%) occur seldom (∼4% of events) and almost all of them are positive; an example of very strong fluctuations of foF2 up to 60% can be an extreme increase in the foF2 on 19.12.2008; (c) the very strong enhancements of foF2 in the NWI maximum can be observed at the low geomagnetic activity, they occur more often during substorms but very seldom during geomagnetic storms. Possible reasons of these properties of NWI are discussed.     

New educational tools to encourage high-school students' activity in stem

Many students have to choose their future profession during their last years in the high school and therefore to choose a university where they will get proper education. That choice may define their professional life for many years ahead or probably for the rest of their lives.Bauman Moscow State Technical University conducts various events to introduce future professions to high-school students. Such activity helps them to pick specialization in line with their interests and motivates them to study key scientific subjects.The paper focuses on newly developed educational tools to encourage high school students’ interest in STEM disciplines. These tools include laboratory courses developed in the fields of physics, information technologies and mathematics. More than 2000 high school students already participated in these experimental courses. These activities are aimed at increasing the quality of STEM disciplines learning which will result in higher quality of training of future engineers.     

Phase asynchrony between coronal index and sunspot numbers

In this paper, the phase asynchrony between coronal index and sunspot numbers is investigated. It is found that, (1) the sunspot numbers begin one month earlier than coronal index, which should mathematically lead to phase asynchrony between them but with a slight effect; (2) the 11-year Schwabe cycle is the only one period with statistical significance for coronal index and sunspot numbers, and the difference between the length of the Schwabe cycle of them should also lead to phase asynchrony between them; (3) although coronal index and sunspot numbers are coherent in low-frequency components corresponding to the 11-year Schwabe cycle, they are asynchronous in phase in high-frequency components; (4) their different definitions and physical meanings may be a major reason why there is a phase asynchrony between them.     

Enzyme activities and membrane lipids in Artemia cysts after a long duration space flight

In the Free Flyer Biostack Experiment (L.D.E.F. mission) investigations have shown that biological objects in a resting state can survive more than 5.5 years of exposure to the space factors in particular microgravity and cosmic rays. We have measured enzyme activities involved in metabolic pathways of sugar and lipid degradation and determined phospholipid composition. Pyruvate kinase and glucose-6-phosphate dehydrogenase activities in space-exposed cysts were higher than in earth controls after 1 hour incubation. In controls, total phospholipids remained unchanged, on the contrary they increased significantly in space-exposed cysts. The rate of metabolism of various phospholipid components was unchanged in controls allowing the development while the level of most of them decreased in space-exposed cysts except for phosphatidylcholine. Enzyme activities (acetylhydrolase, phospholipase A₂ and lyso phospholipase) involved in phospholipid degradation increased; however, activities were much higher in space-exposed cysts. In conclusion, the long duration space flight resulted in an increase of the metabolic activity correlated with a faster development within the first 20 hours of post flight incubation.     

The D-region ion composition and electron density response to strong solar proton events (model simulations)

Fluxes of energetic solar protons penetrate deep into the Earth’s polar cap middle atmosphere. Interacting with molecules of the air they cause additional dissociation and ionization, and the formed NO_x, OH_y and ions enter chemical and ion-molecular reactions. Induced changes of the ionospheric D-layer are modeled by a 1D model of lower ionosphere with chemistry, using neutral species concentrations calculated by a 1D photochemical time-dependent model. Changes of the electron and ion densities, and the most important ionospheric parameters are calculated after SPE with the onset on July 14, 2000 and the results are compared with our results obtained previously for the October 19, 1989 SPE. It is shown that not only electron density increases after SPE, but also the amount of clusters. It is found that the magnitude of the ionospheric response depends on season.     

Relation between the radial speed and theexpansion speed of coronal mass ejections

We have selected 57 limb coronal mass ejections observed by LASCO during the period of January1997 to April 2001. We used the related EIT activity close to the limb to define these CMEs as “limbs”. We measured the radial speed of the leading edge close to the center of these CMEs and the lateral expansion speed of the structures. Comparison of both speeds revealed a high correlation between them, the radial speed being around 88% of the expansion speed of the CME. The expansion speed can also be measured for halo CMEs so that it can be used to infer their radial speed toward earth, which is otherwise inaccessible.     

The day-to-day variability in the mesosphere and lower thermosphere in low latitudes: A study using MF radar

This study presents the analysis of planetary waves (PWs) using daily mean wind velocities for four years (August 2013 to July 2017) of continuous measurements using MF radar over the low latitude Indian region Kolhapur (16.8° N; 74.2° E). The MF radar at Kolhapur was upgraded in 2013. These are the first results of PWs after the upgradation of MF radar. The seasonal and intra-seasonal variabilities of East-West (EW) traveling PWs in the MLT region have been studied. In the present work, the data was analyzed to study the waves with various periodicities (e.g. 3–4, 5–8, 15–17, and 30–60 days). The 3.5 day [Ultra-Fast Kelvin (UFK)] wave shows semiannual variability with burst like wave activity observed during the summer months and December solstice. In addition, it is observed to be stronger in the spring equinoctial period. A strong semiannual oscillation (SAO) has been observed in a 6.5-day wave with peaks near the equinoxes. Similar to SAO over the low latitude MLT region, the wave activity is stronger in April/May than in September/October. The 6.5-day waves are observed to be stronger when the background mean wind is westward. From the analysis, it has been seen that the period before and after the equinoctial period is favorable for the 6.5-day wave propagation. The 16-day wave has no significant seasonal dependence; instead, the waves spread to almost all seasons. The Madden-Julian Oscillations (MJOs) have been observed to be propagating with an average wind speed of ～ 5 m/s when the background mean wind is eastward. The occurrence of MJO is observed during the summer and winter months. These results are the first of their kind in two aspects: first, they show the PWs with enhanced altitude coverage covering up to 110 km, and second, they show the PWs not contaminated due to equatorial electro jet influence.